Enterprise
Truck Rentals

Pickup Truck Rental in Cincinnati

If you need to move furniture or haul supplies, renting a pickup truck through Enterprise will make the process much easier. We have trucks of various sizes to best suit your needs. Reserve a truck online for our lowest rates. 

Explore Rental Pickup Trucks

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FAQs for Renting Trucks in Cincinnati

Yes, all of our pickup trucks can be rented one way. This option is great if you are moving small items a few hours away or taking a cross-state road trip with rugged terrain. A drop charge may apply for one-way rentals, which will be disclosed at the time of reservation. 

Trucks are not available by the hour, but Enterprise does rent out trucks by the day. This gives you the flexibility to use the truck for several hours or a full day. We offer great rates and our easy rental process will get you on the road quickly. 

Although pickup trucks from our Enterprise Rent-A-Car fleet cannot be used to tow, you can go through Enterprise Truck Rental to do so. The Enterprise Truck division offers 3/4 ton pickup trucks and 1-ton pickup trucks that can be used to tow boats, campers, and more. 

Popular Road Trips from Cincinnati

Cincinnati is a great launch point for exploring the Midwest and beyond. From here, you can explore lively cities, historic sites, and beautiful natural areas, all within a day's drive. Whether you are planning a quick getaway or a longer adventure, the open road from Cincinnati offers endless possibilities.

cleveland

Cincinnati to Cleveland

249 mi (3 hr 43 min)

Follow I‑71 north past rolling farmland and Columbus before the route opens toward Lake Erie. In Cleveland, pair waterfront views with icons like the Rock & Roll Hall of Fame, explore University Circle museums, and find great eats in neighborhoods from Ohio City to Tremont.

dayton

Cincinnati to Dayton

54 mi (1 hr 4 min)

Head up I‑75 for a quick hop to Dayton. Aviation history takes center stage at the National Museum of the U.S. Air Force, and the city’s riverside trails and distinct districts make it easy to fill a relaxed day trip with museums and good food. For light traffic runs, this drive can be closer to 50 minutes

indianapolis

Cincinnati to Indianapolis

112 mi (1 hr 44 min)

Cruise west on I‑74 through rural Indiana and arrive in a capital city built for sports and culture. Walk the downtown Canal, visit the Indianapolis Museum of Art at Newfields, and explore lively neighborhoods that surround Monument Circle.

detroit

Cincinnati to Detroit

262 mi (4 hr 5 min)

Follow I‑75 north with a smooth run past Dayton and Toledo toward the Motor City. In Detroit, tour the Detroit Institute of Arts, explore the revitalized riverfront, and dive into music and automotive heritage that shaped American culture. Typical drive time is about four hours under normal conditions.

chicago

Cincinnati to Chicago

296 mi (4 hr 21 min)

Head northwest via I‑74 and I‑65 toward Chicago’s skyline and lakefront. Spend time at Millennium Park, the Art Institute, and along the Riverwalk, then sample neighborhoods for deep‑dish, architecture, and live music across the city.

While the Gateway Arch offers impressive views of the St. Louis cityscape, the new entrance now offers an equally impressive view at ground level. Opened in 2018, the $380-million renovation includes a circular entrance to the Museum of Westward Expansion and add more than 46,000 square feet of exhibition space.

Cincinnati to St. Louis

350 mi (5 hr 1 min)

Travel west across Indiana and Illinois to reach the Gateway Arch and a walkable downtown on the Mississippi. Visit City Museum for a one‑of‑a‑kind urban playground, explore Forest Park’s free museums, and enjoy barbecue and blues in a city with proud traditions. 

One-Way Car Rental

Looking to rent a car for a one-way trip? Enterprise Rent-A-Car offers convenient one-way car rentals. We have a great selection of vehicles for trips across the city, across the country or from the airport.

One-Way Car Rental

Long-Term Car Rental

This is ideal for corporate relocations, temporary work assignments, extended trips, and much more. It can also be used while waiting for a new fleet car. 

Long-Term Car Rental