San Diego Little Italy Car Rental

Car Rental COVID-19 FAQs

Each rental vehicle at Enterprise is thoroughly cleaned between every rental and backed with our Complete Clean Pledge. This includes washing, vacuuming, general wipe down, and sanitizing with a disinfectant that meets leading health authority requirements, with particular attention to more than 20-plus high-touch points. We also extend the Complete Clean Pledge to our shuttles (for airport locations) and neighborhood branches. 

To help protect both customers and employees, we have modified our car rental process. This includes the addition of curbside rentals at our locations to help promote social distancing by getting you quickly on your way while avoiding foot traffic in our locations.
Delivery is also offered at select car rental locations throughout the country. Please contact your rental branch for availability.
Whether you are picking your vehicle up curbside, or if we deliver it to you, we’re committed to maintaining proper distance throughout the process.
Advance Check-In is now available at 100+ U.S locations so you will not need to stop at the rental counter.

You can modify or cancel your reservation via our website or mobile app. We have extended our existing no-fee cancellation policy to include customers with pre-paid rentals booked directly through us. To extend your car rental, you can click “Call to Extend Your Rental” in our mobile app. You can also call your rental branch or 1-855-266-9565 to extend your reservation. 

For more information, please visit our COVID-19 FAQs page.
For additional questions, please visit our main car rental FAQs page.

Location Details for San Diego Little Italy

Location Details


Renting a Car at San Diego Little Italy

Information for Renting a Car in San Diego

This car rental branch is located in the San Diego area near the intersection of Pacific Highway and West Laurel Street. We do not offer pick up or drop off service from San Diego International Airport but we can pick you up from the Cruise Port. Please call the branch when you off ship. There is no after hour drop off for vehicles at this location. Convertibles and 15 passenger vans are particularly popular rentals at this location (based on availability).

Areas Serviced

Little Italy, Harbor Island, Mission Hills, Hillcrest, Old Town, North Downtown

Places of Interest

Los Angeles – approximately a 2.5 hour drive
Palm Springs – approximately a 2.5 hour drive
Las Vegas – approximately a 5 hour drive


Directions to Airport

This branch location is approximately 5 minutes from the San Diego International Airport. Head north on Pacific Highway toward W Laurel St. Turn left at the 1st cross street onto W Laurel St. Take a slight right onto N Harbor Dr and then a slight right onto Airport Terminal Rd to reach the airport.

Nearby Attractions

Cruise Port, Balboa Park, San Diego Zoo, Harbor Island, San Diego airport