Enterprise

San Diego Car Rental

Enterprise Car Rental Locations in San Diego

A rental car from Enterprise Rent-A-Car is perfect for road trips, airport travel, getting around town on weekends and even driving to Disneyland. To transport more people or gear, choose from our large selection of vans including minivans, 12 and 15 passenger vans, cargo vans and sprinter vans. Visit one of our many convenient neighborhood rental locations in San Diego, or find cheap car rental rates at San Diego International Airport (SAN).

Airport Locations

Neighborhood Locations

Things to Do

Explore San Diego

Visit the San Diego Zoo, USS Midway Museum, Balboa Park, Gaslamp Quarter or drive the Pacific Coast Highway to LA.

Benefits of Booking Direct

Low Rates & Quality Service

Earn points towards free rental days with Enterprise Plus and take advantage of our award-winning customer service.

Offers

Find Cheap Car Rental Rates

Get away this weekend in a rental car and enjoy great low rates.

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Popular Rental Cars in San Diego

Find the perfect vehicle for your needs.

suv rental

SUVs

Whether you are going on a weekend family trip or exploring the countryside we are sure to have the ideal SUV for your needs.

Rent an SUV
pickup truck rental

Pickup Truck

Our pickup trucks have the space, power and durability you need for hauling large items or taking a weekend retreat.

luxury car rental

Luxury Cars

Choose from our range of premium cars and SUVs to rent, including convertibles, coupes, hybrids and more.

Rent A Luxury Car

San Diego Car Rental FAQs

For additional questions, please visit our main car rental FAQs page.

Popular Road Trips from San Diego

San Diego is the perfect starting point for road trips that showcase the best of California and beyond. From coastal drives to desert escapes and vibrant cities, these routes offer unforgettable scenery and experiences. Whether you’re planning a quick getaway or a longer adventure, here are six popular road trips starting in America’s Finest City.

las vegas

San Diego to Las Vegas

330 miles (5 hours)

Head northeast through the Mojave Desert to the bright lights of Las Vegas. The route offers unique stops like Joshua Tree National Park and quirky roadside art installations. Once in Vegas, enjoy world-class entertainment, dining, and nightlife or take a detour to Red Rock Canyon for stunning desert views.

san francisco

San Diego to San Francisco

500 miles (8 hours, 30 minutes)

Drive up the California coast for an unforgettable journey to San Francisco. Take the scenic Pacific Coast Highway for ocean views and stops in Malibu, Santa Barbara, and Big Sur. Once you arrive, explore the Golden Gate Bridge, Fisherman’s Wharf, and the city’s iconic neighborhoods.

disneyland

San Diego to Disneyland

95 miles (1 hour, 45 minutes)

Perfect for families, this short trip takes you north to Anaheim for a day of magic at Disneyland Resort. The drive is easy and offers optional stops in charming Orange County beach towns like Laguna Beach or Huntington Beach along the way.

temecula

San Diego to Temecula

60 miles (1 hour, 15 minutes)

Enjoy a quick getaway to Temecula for beautiful countryside views and family-friendly attractions. Stroll through Old Town Temecula, browse local boutiques, and take in the scenic hills that make this area a favorite for day trips.

Borrego Springs

San Diego to Borrego Springs

90 miles (2 hours)

Head east to California’s largest state park for dramatic desert landscapes and outdoor adventure. The route winds through mountain passes before opening up to wide desert vistas. Once there, explore hiking trails, wildflower blooms in spring, and the famous metal sculptures scattered across Borrego Springs.

sedona

San Diego to Sedona, AZ

480 miles (7 hours, 30 minutes)

Head east for a scenic desert adventure to Sedona, Arizona, famous for its striking red rock formations and vibrant arts scene. The drive takes you through wide-open desert landscapes and mountain passes, with optional stops in Phoenix or Flagstaff along the way. Once in Sedona, explore hiking trails, enjoy breathtaking vistas, and experience the unique charm of this Southwestern gem.

San Diego Car Sales

Looking to buy? We sell cars, too. Shop our selection of quality used cars, trucks, vans and SUVs. And, when you’re ready, experience the Enterprise customer service you know and expect.

San Diego Exotic Car Rental

In San Diego, we offer exotic sports cars, luxury sedans and SUVs, and have one of the largest selections of exotic and premium vehicle rentals available.

San Diego Truck Rental

Need a truck? Our moving trucks, cargo vans and towing equipped pickup trucks are available for daily, weekly or monthly rental.