Enterprise
Truck Rentals

Pickup Truck Rental in San Francisco

If you need to move furniture or haul supplies, renting a pickup truck through Enterprise will make the process much easier. We have trucks of various sizes to best suit your needs. Reserve a truck online for our lowest rates. 

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FAQs for Renting Trucks in San Francisco

Yes, all of our pickup trucks can be rented one way. This option is great if you are moving small items a few hours away or taking a cross-state road trip with rugged terrain. A drop charge may apply for one-way rentals, which will be disclosed at the time of reservation. 

Trucks are not available by the hour, but Enterprise does rent out trucks by the day. This gives you the flexibility to use the truck for several hours or a full day. We offer great rates and our easy rental process will get you on the road quickly. 

Although pickup trucks from our Enterprise Rent-A-Car fleet cannot be used to tow, you can go through Enterprise Truck Rental to do so. The Enterprise Truck division offers 3/4 ton pickup trucks and 1-ton pickup trucks that can be used to tow boats, campers, and more. 

Popular Road Trips from San Francisco

San Francisco is a launchpad for unforgettable road trips across the West Coast. Whether you're heading to alpine lakes, coastal cities, or vibrant urban centers, these scenic drives offer a mix of natural beauty and cultural discovery. From weekend escapes to longer adventures, here are six popular road trips starting in the City by the Bay.

lake tahoe

San Francisco to Lake Tahoe

230 miles (4 hours, 30 minutes)

Head east into the Sierra Nevada mountains for a refreshing alpine escape. The drive passes through Sacramento and climbs into forested terrain. Once at Lake Tahoe, enjoy hiking, boating, or skiing depending on the season, with stunning lake views at every turn.

los angeles

San Francisco to Los Angeles

460 miles (10 hours)

Take the scenic coastal route to Los Angeles via Highway 1 and US‑101. This drive includes stops in Monterey, Carmel-by-the-Sea, and Santa Barbara. Once in LA, explore iconic neighborhoods, beaches, and entertainment districts across the sprawling city.

san diego

San Francisco to San Diego

500 miles (8 hours, 30 minutes)

Make your way down the California coast to sunny San Diego. The route offers ocean views and charming towns like Pismo Beach and Laguna Beach. Once there, enjoy Balboa Park, the historic Gaslamp Quarter, and miles of sandy shoreline.

seattle

San Francisco to Seattle

840 miles (13 hours, 30 minutes)

For a longer adventure, head to Seattle through the Pacific Northwest. The drive takes you through Oregon’s Willamette Valley and past Mount Rainier. Once in Seattle, enjoy waterfront views, iconic landmarks like the Space Needle, and a thriving arts and tech scene.

yosemite national park

San Francisco to Yosemite

170 miles (3 hours, 20 minutes)

Escape to one of California’s most iconic natural wonders. The drive to Yosemite takes you through the Central Valley and into the Sierra foothills. Once inside the park, explore towering waterfalls, granite cliffs, and scenic trails in Yosemite Valley, or venture to Glacier Point for panoramic views.

sacramento

San Francisco to Sacramento

90 miles (1 hour, 45 minutes)

Take a quick trip inland to California’s capital city. The drive is smooth and scenic, passing through the East Bay and Central Valley. Once in Sacramento, explore historic Old Town, visit the California State Capitol, and enjoy riverfront dining along the Sacramento River.

One-Way Car Rental

Looking to rent a car for a one-way trip? Enterprise Rent-A-Car offers convenient one-way car rentals. We have a great selection of vehicles for trips across the city, across the country or from the airport.

One-Way Car Rental

Long-Term Car Rental

This is ideal for corporate relocations, temporary work assignments, extended trips, and much more. It can also be used while waiting for a new fleet car. 

Long-Term Car Rental