A rental car from Enterprise Rent-A-Car is perfect for road trips, airport travel, getting around town on weekends and even driving to Disneyland. To transport more people or gear, choose from our large selection of vans including minivans, 12 and 15 passenger vans, cargo vans and sprinter vans. Visit one of our many convenient neighborhood rental locations in San Diego, or find cheap car rental rates at San Diego International Airport (SAN).
San Diego Road Trips
A road trip is the perfect way to visit multiple cities and make memories along the way. Whether you want to visit a bustling city, serene landscape, or both, you've got plenty of destinations to choose from. Load up your rental car and experience some of America's greatest attractions.
Drive from the sandy beaches of San Diego through national forests and desert flat lands on the way to the urban oasis, Las Vegas.
Make the drive from San Diego to Disneyland and see all the best stops along the way using this driving itinerary.
Looking to get from San Diego to San Francisco using the fastest, most direct route? This is the road trip itinerary for you.
Rent a convertible and hit the road as you take this laid-back road trip from Los Angeles to San Diego. Enjoy the beautiful coastline and the incredible weather of Southern California.
Explore the landscapes from sand dunes and sandy beaches to the urban oasis and national forests when driving from Las Vegas to San Diego.
The minimum age to rent a car from Enterprise in San Diego is 21 years of age. A young renter fee may be applied if you are between 21-24. To see the exact rate please start a reservation above. For more info on our car rental under 25 policy please see our FAQ section.
Debit cards are accepted at San Diego airport and non-airport locations. Please note that there may be additional restrictions if you are planning on driving to Mexico. For more details please visit the payment methods and driving to Mexico/Canada FAQs.
Need a truck? Our moving trucks, cargo vans and towing equipped pickup trucks are available for daily, weekly or monthly rental.
We have more than 250 makes and models of quality used cars, trucks, vans and SUVs to choose from—all at great prices and backed by one of the industry's best used car warranties.