Drive From Nashville to Charleston

Whether you’re on the hunt for a family-friendly getaway or a coastal home-office, Charleston can be the place to be. In these uncertain times, many of us are rethinking the way we travel and the added safety precautions that must be considered along the way. A rental car from Enterprise can alleviate many of these concerns, so you can get to Charleston safely.

Drive time from Nashville to Charleston: approx. 8 hours (Driving Directions)

Distance: approx. 551 miles

Rent with Confidence from Enterprise

Learn about our commitment to protecting the well-being of customers and employees, including our Complete Clean Pledge.

Why Driving May Be the Best Way to Get There

  • Travel at your own pace and on your own schedule
  • Ensure social distancing and limit interactions along the way
  • More complete control of surroundings while traveling 
  • Pay a total price for the vehicle vs. buying a plane/train/bus ticket for every passenger 
  • Variety of vehicle choices for any road trip
  • Flexible travel with free cancellation

Benefits of renting a car vs. using a personal vehicle

  • Reduce wear-and-tear and/or mileage on your own vehicle
  • Enjoy a late model year vehicle to ensure the most optimal comfort, convenience and the latest technology
  • Minivans and large SUVs available for larger groups
  • Extra cargo space to haul camping equipment or hiking gear
  • Add-ons such as car seats, GPS/navigation system or ski racks are available (reserve while booking online)

Driving Resources

COVID-19 Car Rental FAQs

Check out our COVID-19 FAQs for more information on Enterprise hours of operation, upcoming and existing reservations, Enterprise Plus and what steps we're taking to keep employees and customers safe with our Clean Car Pledge.

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Planning a Road Trip During COVID-19

Are you thinking about taking a road trip during COVID-19? Check out our tips and resources to consider before you leave.

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Free Single Upgrade

Stretch your legs – and your travel budget – with a free upgrade at participating locations.

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Popular Vehicle Types

SUVs

Our SUVs offer flexibility with seating capacity, power, and luggage room. Find the ideal SUV for your next weekend family trip or exploring the countryside.
Rent an SUV

Trucks

Looking to haul large items for DIY projects or going on a weekend retreat? A pickup truck has space, power and durability ideal for your project or trip.
Rent a Truck

Vans

Need extra room for people, luggage, or cargo or both? Our minivans and passenger vans can seat up to 7 and 15 people and are great for family vacations or large groups.
Rent a Van

Nashville Drives and Road Trips