Road Trip from San Francisco to San Diego on Highway 99

When envisioning the drive from San Francisco to San Diego, the long coastal stretches and beautiful views of the Pacific Ocean are what often come to mind. The costal drive follows the Pacific Coast Highway (PCH), which we have road trip itineraries for. However, there is also the option to drive inland along California Highway 99. Regularly overlooked for the famous PCH, taking the inland route offers a different, but nonetheless adventurous and fun, view of The Golden State. Fuel up and follow this inland road trip route from San Francisco to San Diego to see more of the best California has to offer. Be prepared for the open road by visiting our checklist of road trip essentials.


Drive Time from San Francisco to San Diego: approximately 10 hours
Distance from San Francisco to San Diego: approximately 550 miles
Best car for this road trip: Full Size

 

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